Human Basophil Releasability. VIII. Increased Basophil Releasability in Patients with Scleroderma
نویسندگان
چکیده
منابع مشابه
Effect of montelukast on basophil releasability in patients with asthma.
BACKGROUND The anti-inflammatory effect of montelukast, a leukotriene receptor antagonist, in patients with bronchial asthma is not entirely clear. Basophils can release a variety of mediators, including histamine and leukotriens, which most likely play an active role in the late allergic response. OBJECTIVES To study the effect of montelukast (10 mg/day) on histamine and cysteinyl leukotrien...
متن کاملComparison of basophil histamine releasability between atopic and nonatopic asthmatics.
To compare the mediator releasability between atopic and nonatopic asthmatics, we measured basophil histamine releasability (BaHR) using a calcium-ionophore A23187 and anti-IgE in 137 subjects who were treated at Seoul National University Hospital. Subjects were categorized into atopic (group AA, n=77) or nonatopic asthmatics (group NA, n=32), or normal controls (group NC, n=28). Serum total Ig...
متن کاملFood-dependent exercise-induced anaphylaxis: possible impact of increased basophil histamine releasability in hyperosmolar conditions.
We present a case of anaphylactic shock induced by exercise following celery ingestion. The possible mechanism of food-dependent exercise-induced anaphylaxis (FDEIA) and the laboratory tests for its diagnosis are discussed. We evaluated spontaneous, celery-allergen-induced, and anti-FcepsilonRI-antibody-induced histamine release from basophils obtained from the patient, 2 celery-allergic contro...
متن کاملIncreased Releasability of Skin Mast Cells after Exercise in Patients with Exercise-induced Asthma
The role of lung mast cells in exercise-induced asthma (EIA) is controversial. To investigate whether the skin mast cell releasability is increased after exercise in EIA, 49 young atopic men with or without asthma took part in a free-running test for 6 min and were given skin prick tests using morphine, a mast cell secretagogue, before and after the exercise. The mean diameters of the wheal ind...
متن کاملBasophil production.
Factors influencing basophil production from the bone marrow of ovalbumin (OA)-sensitized guinea pigs have been examined in vitro. Autologous co-cultures of marrow and spleen cells from OA-immune animals contained significantly higher numbers of basophils after 7 d of liquid culture in the presence of OA, compared with control co-cultures or with marrow cultures alone (P < 0.005). Basophils inc...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1991
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780341013